Newswise Feature Channel: Stem Cells

Cedars-Sinai Marks 15 Years of Regenerative Medicine

Cedars-Sinai — Fri, 18 Apr 2025 11:00:59 EST

The Cedars-Sinai Board of Governors Regenerative Medicine Institute is marking its 15th anniversary by further expanding its commitment to research, development of cell-based human models and therapies, and education with three new leadership appointments and the creation of a master's degree program.

Key Enzyme in Lipid Metabolism Linked to Immune System Aging

University of California San Diego — Thu, 17 Apr 2025 16:30:02 EST

New research suggests that decreased activity of ELOVL2 -- a key enzyme in lipid metabolism -- accelerates white blood cell aging and alters genes associated with the onset of blood cancers.

Reprogramming Cancer Cells to Treat an Aggressive Type of Leukemia

Ludwig Cancer Research — Wed, 16 Apr 2025 17:15:09 EST

A Ludwig Cancer Research study has identified a novel strategy for treating acute myelogenous leukemia (AML), an aggressive blood cancer for which the median survival time following diagnosis remains just 8.5 months.

Guinea Pigs: A Promising Animal Model to Study the Human Embryo

Universite de Montreal — Tue, 15 Apr 2025 18:40:20 EST

CRCHUM researchers reveal that the guinea pig pre-implantation embryo is very similar to the human embryo, spurring a better understanding of infertility and early human development.

Hidden Forces Shape Plants From the Inside Out

Universite de Montreal — Wed, 09 Apr 2025 18:30:27 EST

UdeM scientists use a combination of experimental data and modelling to reveal how physical forces help plants to generate their complex 3D shapes.

UCLA Researchers Identify Precision Medicine Approach for Preventing Kidney Failure

University of California, Los Angeles (UCLA), Health Sciences — Wed, 09 Apr 2025 14:00:00 EST

UCLA researchers have identified collagen as a key factor in kidney fibrosis, revealing its potential as a biomarker to predict chronic kidney disease progression. A repurposed anti-cancer drug, Cilengitide, was found to reduce kidney scarring and slow disease progression in preclinical models, suggesting a possible precision medicine approach for high-risk patients.

Ventris Medical Receives Additional FDA Clearance for Backpack(r) Bone Graft in the Intervertebral Disc Space

Ventris Medical — Tue, 08 Apr 2025 07:05:46 EST

Ventris Medical, a privately held orthobiologics and tissue regeneration company, today announced that the United States Food and Drug Administration has granted 510(k) clearance for Backpack(r) (Porous Biologic Scaffold, K250556) for use in the Intervertebral Disc Space.

2025 Surinderjit Singh Young Lectureship Award Winner

American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM) — Mon, 07 Apr 2025 22:45:07 EST

The American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) is excited to announce Crystal Yeo, MB BChir, PhD, as the 2025 Surinderjit Singh Young Lectureship Award recipient.

Curious by Nature: Dr. Gilbert Bernier - Can Stem Cells Cure Blindness?

Newswise — Fri, 04 Apr 2025 17:50:37 EST

Dr. Gilbert Bernier, a neuroscientist and professor at the University of Montreal who is pushing the boundaries of regenerative medicine.

Lurie Children's Transplant Program Highlights National Donate Life Month

Ann and Robert H. Lurie Children's Hospital of Chicago — Fri, 04 Apr 2025 12:00:20 EST

Every year, thousands of children in the United States require life-saving organ transplants. provides comprehensive care to children requiring organ transplants, including heart, kidney, liver, smal...

NK Cells Complexed with Bispecific Antibody Yield High Response Rates in Patients with Lymphoma

University of Texas MD Anderson Cancer Center — Fri, 04 Apr 2025 05:00:00 EST

A novel cell therapy approach using cord blood-derived natural killer (NK) cells pre-complexed with AFM13, or acimtamig, a CD30/CD16A bispecific antibody, was safe and generated strong response rates for patients with refractory CD30-positive lymphomas, according to a new study from The University of Texas MD Anderson Cancer Center.

New Method Creates 854x More Mitochondria, Offering Hope for Cartilage Regeneration

Chinese Academy of Sciences — Mon, 31 Mar 2025 06:10:32 EST

Scientists have unveiled a revolutionary method for mass-producing high-quality human mitochondria, potentially transforming treatments for degenerative diseases. By refining stem cell culture conditions, researchers achieved an extraordinary 854-fold increase in mitochondrial production while significantly enhancing energy output.

Regulation of lncRNA-ENST on Myc-Mediated Mitochondrial Apoptosis in Mesenchymal Stem Cells: In Vitro Evidence Implicated for Acute Lung Injury Therapeutic Potential

World Journal of Stem Cells — Wed, 26 Mar 2025 12:00:38 EST

BACKGROUNDAcute lung injury (ALI) is a fatal and heterogeneous disease. While bone marrow mesenchymal stem cells (BMSCs) have shown promise in ALI repair, their efficacy is compromised by a high apoptotic percentage. Preliminary findings ha

Emerging Role of Mesenchymal Stem Cell-Derived Exosomes in the Repair of Acute Kidney Injury

World Journal of Stem Cells — Wed, 26 Mar 2025 12:00:25 EST

Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid deterioration in kidney function and has a significant impact on patient health and survival. Mesenchymal stem cells (MSCs) have the potential to enhance renal functi

Fat Mass and Obesity-Associated Protein in Mesenchymal Stem Cells Inhibits Osteoclastogenesis via lnc NORAD/miR-4284 Axis in Ankylosing Spondylitis

World Journal of Stem Cells — Wed, 26 Mar 2025 12:00:19 EST

BACKGROUNDAnkylosing spondylitis (AS) is recognized as a long-term inflammatory disorder that leads to inflammation in the spine and joints, alongside abnormal bone growth. In previous studies, we reported that mesenchymal stem cells (MSCs)

Immunomodulatory Effects and Clinical Application of Exosomes Derived From Mesenchymal Stem Cells

World Journal of Stem Cells — Wed, 26 Mar 2025 12:00:14 EST

Exosomes (Exos) are extracellular vesicles secreted by cells and serve as crucial mediators of intercellular communication. They play a pivotal role in the pathogenesis and progression of various diseases and offer promising avenues for the

Cyclodextrin Host-Guest Complex to Facilitate Sinomenine-Based Osteoporosis Therapy

World Journal of Stem Cells — Wed, 26 Mar 2025 12:00:12 EST

Xiao et al reported on the natural product sinomenine (SIN), which is a traditional Chinese medicine for treating osteoporosis via its modulation of autophagy; however, SIN was dissolved in dimethyl sulfoxide prior to administration, which

DNA Methyltransferase 1/miR-342-3p/Forkhead box M1 Signaling Axis Promotes Self-Renewal in Cervical Cancer Stem-Like Cells in Vitro and Nude Mice Models

World Journal of Stem Cells — Wed, 26 Mar 2025 12:00:11 EST

BACKGROUNDCervical cancer (CC) stem cell-like cells (CCSLCs), defined by the capacity of differentiation and self-renewal and proliferation, play a significant role in the progression of CC. However, the molecular mechanisms regulating thei

MiR-21-5p-enriched exosomes from hiPSC-derived cardiomyocytes exhibit superior cardiac repair efficacy compared to hiPSC-derived exosomes in a murine MI model

World Journal of Stem Cells — Wed, 26 Mar 2025 12:00:06 EST

BACKGROUNDHeart disease remains a leading cause of mortality worldwide, with existing treatments often failing to effectively restore damaged myocardium. Human-induced pluripotent stem cells (hiPSCs) and their derivatives offer promising th

Efficacy Equivalence but Hidden Hurdles: Can Serum-Free Human Umbilical Cord Mesenchymal Stem Cells Translate to Clinically Superior Osteoarthritis Therapy

World Journal of Stem Cells — Wed, 26 Mar 2025 12:00:03 EST

This article discusses the study by Xiao et al, which investigated the therapeutic efficacy of serum-free cultured human umbilical cord mesenchymal stem cells (N-hUCMSCs) in a mouse model of knee osteoarthritis. The results showed that N-hU