Newswise Feature Channel: Ethics and Research Methods

New Innovation Alliance Aims to Drive New Med Tech Ventures In Region

University of Maryland School of Medicine — Mon, 28 Apr 2025 16:40:43 EST

A new collaboration bringing entrepreneurs and investors together with physician-scientists, surgeons, and medical technologists promises to launch the Baltimore region as a major national hub for new biomedical ventures and start-up companies.

Penn Medicine Breaks Ground on Fourth Proton Therapy Center

Perelman School of Medicine at the University of Pennsylvania — Mon, 28 Apr 2025 15:30:00 EST

Today, Penn Medicine celebrated the groundbreaking of the Roberts Proton Therapy Center at Penn Presbyterian Medical Center in University City, which is expected to open for patient care in late 2027.

Researchers Say a Genetic Mutation and Evolutionary Trick Makes Horses Athletic, Finding May Spur Treatments for Human Disease

Johns Hopkins Medicine — Mon, 28 Apr 2025 10:35:34 EST

How did horses become some of the greatest athletes in the animal kingdom? Researchers at Johns Hopkins Medicine may have found the answer, pinpointing a genetic mutation and evolutionary process that occurred millions of years ago, which appears to have optimized horses' speeds and stamina.

A Social Media Study of Portrayals of Bipolar Disorders on YouTube: Content and Thematic Analyses

Journal of Medical Internet Research — Mon, 28 Apr 2025 10:20:50 EST

Background: Individuals with mental disorders frequently use YouTube to express themselves, reach an audience, or as a means of understanding their condition. Testimonies posted on YouTube provide longer and richer perspectives than ...

Expert and Interdisciplinary Analysis of AI-Driven Chatbots for Mental Health Support: Mixed Methods Study

Journal of Medical Internet Research — Mon, 28 Apr 2025 10:20:10 EST

Background: Recent years have seen an immense surge in the creation and use of chatbots as social and mental health companions. Aiming to provide empathic responses in support of the delivery of personalized support, these tools are ...

Sustainability and Time Trends in Electronic Patient-Reported Outcome Assessment in Routine Cancer Care: Systematic Scoping Review and Follow-Up Survey

Journal of Medical Internet Research — Mon, 28 Apr 2025 10:15:42 EST

Background: Routine electronic assessment of patient-reported outcomes (ePROs) can improve cancer care; yet, its implementation in routine practice and long-term sustainability remain unclear. Understanding these aspects is critical ...

Digital Health Interventions to Prevent Type 2 Diabetes Mellitus: Systematic Review

Journal of Medical Internet Research — Mon, 28 Apr 2025 10:10:20 EST

Background: Digital health interventions (DHIs) have rapidly evolved and significantly revolutionized the health care system. The quadruple aims of health care (improving population health, enhancing consumer experience, enhancing he...

The Role of Digital Opinion Leaders in Dengue Prevention Through Health Promotion and Public Health Collaboration: Qualitative Semistructured Interview Study

Journal of Medical Internet Research — Mon, 28 Apr 2025 09:30:50 EST

Background: Dengue fever is a significant public health concern. The advent of social media has introduced digital opinion leaders (DOLs), health care professionals with substantial online followings who play a pivotal role in dissem...

Impact of Computer-Mediated Versus Face-to-Face Motivational-Type Interviews on Participants' Language and Subsequent Cannabis Use: Randomized Controlled Trial

Journal of Medical Internet Research — Mon, 28 Apr 2025 09:25:22 EST

Background: Motivational interviewing (MI) is frequently used to facilitate behavior change. The use of change talk during motivational interviews can predict subsequent behavior change. However, no studies have compared the informat...

AACR: HER2 targeted therapy shows promise in previously treated lung cancers

University of Texas MD Anderson Cancer Center — Mon, 28 Apr 2025 09:00:00 EST

* Zongertinib, a HER2-targeted therapy made by Boehringer Ingelheim, demonstrated promising results in HER2-mutant lung cancer

Anti-inflammatory Drug Reverses Periodontal Damage via Cellular Cleanup

Chinese Academy of Sciences — Mon, 28 Apr 2025 08:30:26 EST

A recent study reveals that dimethyl fumarate (DMF), a compound already approved for other inflammatory diseases, can prevent and alleviate periodontal tissue damage. The research demonstrates that DMF significantly shifts immune cell behavior, promoting anti-inflammatory macrophages and restoring mitochondrial health by enhancing mitophagy--a cellular process that removes damaged mitochondria. The drug achieves this through regulation of Tu translation elongation factor (TUFM), a protein critical to mitochondrial function. This breakthrough suggests a new therapeutic approach for periodontitis by targeting mitochondrial quality control and immune modulation rather than relying solely on traditional plaque-removal strategies.

AACR: Topical Treatment Offers Relief From Painful Skin Rash Caused by Targeted Cancer Therapy

University of California, Los Angeles (UCLA), Health Sciences — Sun, 27 Apr 2025 16:30:00 EST

UCLA researchers demonstrated that a novel topical BRAF inhibitor gel called LUT014 significantly reduces the severity of an acne-like rash, a common and painful side effect experienced by patients undergoing anti-EGFR therapies for colorectal cancer.

Ludwig Cancer Research scientists to present at AACR Annual Meeting

Ludwig Cancer Research — Fri, 25 Apr 2025 18:25:54 EST

Ludwig Cancer Research released today the full scope of research to be presented by Ludwig-affiliated scientists at the American Association for Cancer Research (AACR) Annual Meeting 2025, which will be held online and in person in Chicago, from April 25 to April 30.

Episode 308 -- Corporate Governance

University of Michigan Ross School of Business — Fri, 25 Apr 2025 18:20:14 EST

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AACR 2025: Colon Cancer Risk Reduction, Predicting Melanoma Spread and New Drug Therapies Among Ohio State Findings

Ohio State University Wexner Medical Center — Fri, 25 Apr 2025 13:00:00 EST

A new targeted drug treatment for small cell lung cancer, understanding how obesity drives endometrial cancer, and predicting early-stage melanoma spread are among the research topics being presented by scientists with The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at the American Association for Cancer Research Annual Meeting April 25-30 in Chicago.

Head and neck, breast, lung and survivorship studies headline Dana-Farber research at AACR Annual Meeting 2025

Dana-Farber Cancer Institute — Fri, 25 Apr 2025 13:00:00 EST

Numerous studies conducted by researchers at Dana-Farber Cancer Institute report progress for cancers including head and neck cancer, metastatic breast cancer and lung cancer.

Even Light Exercise Could Help Slow Cognitive Decline in People at Risk of Alzheimer's

University of California San Diego — Thu, 24 Apr 2025 09:10:00 EST

In a landmark clinical trial, coordinated by the Alzheimer's Disease Cooperative Study at UC San Diego, people at risk for Alzheimer's who exercised at low or moderate-high intensity showed less cognitive decline when compared to those receiving usual care.

Multisequence 3-T Image Synthesis from 64-mT Low-Field-Strength MRI Using Generative Adversarial Networks in Multiple Sclerosis

Perelman School of Medicine at the University of Pennsylvania — Tue, 22 Apr 2025 20:00:18 EST

Argonne Leverages AI and Supercomputing to Revolutionize Cancer Research

Argonne National Laboratory — Tue, 22 Apr 2025 17:35:46 EST

Researchers at Argonne National Laboratory are transforming cancer research by using AI and supercomputing to accelerate drug discovery and improve drug response predictions.

UCLA Investigators Highlight Innovations in Prostate and Bladder Cancer, AI, and Patient-Centered Care at AUA 2025

University of California, Los Angeles (UCLA), Health Sciences — Mon, 21 Apr 2025 20:05:04 EST

Investigators from the David Geffen School of Medicine at UCLA and the UCLA Health Jonsson Comprehensive Cancer Center will be involved in more than four dozen sessions at the annual meeting of the American Urological Association from April 26 to 29.