Latest news from Perelman School of Medicine at the University of Pennsylvania on Newswise en-us Copyright 2025 Newswise 115 31 / /images/newswise-logo-rss.gif /articles/new-ai-technique-can-uncover-antiviral-compounds-using-limited-data/?sc=rsin /articles/new-ai-technique-can-uncover-antiviral-compounds-using-limited-data/?sc=rsin Tue, 29 Apr 2025 11:00:00 EST Artificial intelligence algorithms have now been combined with traditional laboratory methods to uncover promising drug leads against human enterovirus 71 (EV71), the pathogen behind most cases of hand, foot and mouth disease. The study, published today in Cell Reports Physical Science by researchers at the Perelman School of Medicine at the University of Pennsylvania, showed that reliable antiviral predictions can be made even when only a modest amount of experimental data are available. Perelman School of Medicine at the University of Pennsylvania /articles/penn-medicine-breaks-ground-on-fourth-proton-therapy-center/?sc=rsin /articles/penn-medicine-breaks-ground-on-fourth-proton-therapy-center/?sc=rsin Mon, 28 Apr 2025 15:30:00 EST Today, Penn Medicine celebrated the groundbreaking of the Roberts Proton Therapy Center at Penn Presbyterian Medical Center in University City, which is expected to open for patient care in late 2027. Perelman School of Medicine at the University of Pennsylvania /articles/new-medicare-program-could-dramatically-improve-affordability-for-cancer-drugs-if-patients-enroll/?sc=rsin /articles/new-medicare-program-could-dramatically-improve-affordability-for-cancer-drugs-if-patients-enroll/?sc=rsin Fri, 25 Apr 2025 16:00:00 EST Even for patients covered by Medicare, annual out-of-pocket costs for lifesaving cancer treatments taken in pill form have often exceeded $10,000--until recently. Thanks to changes in Medicare Part D introduced by the Inflation Reduction Act (IRA) that took effect in 2025, annual out-of-pocket drug costs for all beneficiaries are now capped at $2,000. Perelman School of Medicine at the University of Pennsylvania /articles/multisequence-3-t-image-synthesis-from-64-mt-low-field-strength-mri-using-generative-adversarial-networks-in-multiple-sclerosis/?sc=rsin /articles/multisequence-3-t-image-synthesis-from-64-mt-low-field-strength-mri-using-generative-adversarial-networks-in-multiple-sclerosis/?sc=rsin Tue, 22 Apr 2025 20:00:18 EST Perelman School of Medicine at the University of Pennsylvania /articles/nudge-boosts-statin-prescribing-means-fewer-pharmacy-trips/?sc=rsin /articles/nudge-boosts-statin-prescribing-means-fewer-pharmacy-trips/?sc=rsin Tue, 22 Apr 2025 19:55:56 EST Statins are lifesaving to those with high cholesterol, but patients don't always take them. A nudge that increased long-term prescriptions could be key Perelman School of Medicine at the University of Pennsylvania /articles/children-face-elevated-kidney-heart-and-gut-risks-for-years-after-covid-infection/?sc=rsin /articles/children-face-elevated-kidney-heart-and-gut-risks-for-years-after-covid-infection/?sc=rsin Tue, 22 Apr 2025 18:05:53 EST Findings included elevated risks for chronic organ disease among children, and revealed some racial differences in long COVID risks Perelman School of Medicine at the University of Pennsylvania /articles/first-new-subtype-of-castleman-disease-discovered-in-45-years/?sc=rsin /articles/first-new-subtype-of-castleman-disease-discovered-in-45-years/?sc=rsin Tue, 22 Apr 2025 09:00:08 EST A newly identified subtype of Castleman disease will help diagnose and properly treat thousands of patients who have been caught between existing classification systems, marking the first major discovery of its kind in 45 years. "Oligocentric Castleman Disease" (OligoCD) has been found to be a distinct clinical entity, different from the two previously identified classifications of Castleman Disease. The findings, which redefine the understanding of this rare immune disorder that affects an estimated 4,300 to 5,200 Americans, are published this week in Blood Advances by researchers from the Perelman School of Medicine at the University of Pennsylvania. Perelman School of Medicine at the University of Pennsylvania /articles/covid-vaccine-protected-kids-from-long-covid/?sc=rsin /articles/covid-vaccine-protected-kids-from-long-covid/?sc=rsin Tue, 22 Apr 2025 08:45:13 EST Instead of special protection against long COVID, vaccines kept children and adolescents from developing the condition by blocking COVID-19 infections in the first place Perelman School of Medicine at the University of Pennsylvania /articles/penn-medicine-at-the-aacr-annual-meeting-2025/?sc=rsin /articles/penn-medicine-at-the-aacr-annual-meeting-2025/?sc=rsin Mon, 21 Apr 2025 10:15:38 EST Penn researchers will present on the latest advances in cancer science and medicine at the American Association for Cancer Research Annual Meeting. Perelman School of Medicine at the University of Pennsylvania /articles/wyss-donation-creates-penn-orthoplastic-surgery-hub/?sc=rsin /articles/wyss-donation-creates-penn-orthoplastic-surgery-hub/?sc=rsin Fri, 18 Apr 2025 10:50:59 EST The $4.9 million donation will create the Wyss Orthoplastic Global Education and Innovation Hub at Penn, creating opportunities for fellowships, education, and research Perelman School of Medicine at the University of Pennsylvania /articles/shelley-berger-phd-honored-by-aacr-for-cancer-research/?sc=rsin /articles/shelley-berger-phd-honored-by-aacr-for-cancer-research/?sc=rsin Mon, 14 Apr 2025 19:10:46 EST Shelley L. Berger, PhD, FAACR, has been recognized for her outstanding contributions to cancer research by the American Association for Cancer Research (AACR) with the 2025 AACR-Women in Cancer Research Charlotte Friend Lectureship. Perelman School of Medicine at the University of Pennsylvania /articles/penn-medicine-breaks-ground-on-innovative-outpatient-center-in-montgomery-county/?sc=rsin /articles/penn-medicine-breaks-ground-on-innovative-outpatient-center-in-montgomery-county/?sc=rsin Fri, 11 Apr 2025 18:00:59 EST Penn Medicine leaders and regional community representatives broke ground today on a four-story, 162,000-square-foot multispecialty outpatient facility that will expand options for patients to receive advanced care in Montgomery and Bucks counties. Perelman School of Medicine at the University of Pennsylvania /articles/penn-medicine-cares-grant-helps-patients-share-their-own-health-care-story/?sc=rsin /articles/penn-medicine-cares-grant-helps-patients-share-their-own-health-care-story/?sc=rsin Thu, 03 Apr 2025 19:30:14 EST The funds will be used to help train volunteer medical students, who will then be paired with patients referred from palliative care, oncology, family medicine, and social work. Perelman School of Medicine at the University of Pennsylvania /articles/laughing-gas-an-old-drug-s-new-trick-to-fight-depression/?sc=rsin /articles/laughing-gas-an-old-drug-s-new-trick-to-fight-depression/?sc=rsin Thu, 03 Apr 2025 10:25:22 EST Nitrous oxide--better known as "laughing gas"--can potentially transform treatment for tough-to-beat depression. This centuries-old anesthetic gas targeted specific brain cells in mice and quickly reduced symptoms, according to new research from the Perelman School of Medicine at the University of Pennsylvania, reported today in Nature Communications. Perelman School of Medicine at the University of Pennsylvania /articles/doylestown-health-joins-university-of-pennsylvania-health-system/?sc=rsin /articles/doylestown-health-joins-university-of-pennsylvania-health-system/?sc=rsin Tue, 01 Apr 2025 10:15:00 EST Doylestown Health (DH) officially joined the University of Pennsylvania Health System (UPHS) today, strengthening the two organizations' shared commitment to delivering the most advanced, convenient and compassionate care to patients and families across Philadelphia's northern suburbs. Perelman School of Medicine at the University of Pennsylvania /articles/meniscus-injuries-may-soon-be-treated-by-customizable-hydrogel/?sc=rsin /articles/meniscus-injuries-may-soon-be-treated-by-customizable-hydrogel/?sc=rsin Fri, 28 Mar 2025 19:00:59 EST A new 3D printed customizable hydrogel performed well in preclinical trials with several different types of meniscal tears Perelman School of Medicine at the University of Pennsylvania /articles/new-technology-is-poised-to-bring-gene-therapy-to-common-chronic-diseases/?sc=rsin /articles/new-technology-is-poised-to-bring-gene-therapy-to-common-chronic-diseases/?sc=rsin Tue, 25 Mar 2025 18:05:40 EST A breakthrough in safely delivering therapeutic DNA to cells could transform treatment for millions suffering from common chronic diseases like heart disease, diabetes, and cancer. Perelman School of Medicine at the University of Pennsylvania /articles/anti-obesity-medication-boosts-weight-loss-when-behavioral-therapy-falls-short/?sc=rsin /articles/anti-obesity-medication-boosts-weight-loss-when-behavioral-therapy-falls-short/?sc=rsin Tue, 18 Mar 2025 17:40:49 EST Adding an anti-obesity medication just one month after behavioral therapy begins--rather than waiting the currently recommended six months--can more than double weight loss for patients who struggle initially with lifestyle changes alone, according to new research published in Nature Medicine from a team at the Perelman School of Medicine at the University of Pennsylvania. Perelman School of Medicine at the University of Pennsylvania /articles/small-incentives-drive-lasting-seatbelt-habits-cut-unbuckled-trips-by-a-third/?sc=rsin /articles/small-incentives-drive-lasting-seatbelt-habits-cut-unbuckled-trips-by-a-third/?sc=rsin Fri, 14 Mar 2025 21:00:20 EST We've all heard "Click It, or Ticket" as a reminder to buckle up in the car, but "Click It and Win It!" appears to be an effective approach for sustaining consistent seatbelt use among drivers. When drivers were promised a share of $125 weekly prize money for maintaining perfect seatbelt use streaks, they established good, long-lasting habits. Driving without a seatbelt decreased 26% relative to the control during the incentive program and was 33% than the control even after the program ended, according to research from the Perelman School of Medicine at the University of Pennsylvania, published in the American Journal of Public Health. Perelman School of Medicine at the University of Pennsylvania /articles/immunotherapy-may-boost-kras-targeted-therapy-in-pancreatic-cancer/?sc=rsin /articles/immunotherapy-may-boost-kras-targeted-therapy-in-pancreatic-cancer/?sc=rsin Fri, 14 Mar 2025 20:40:54 EST Adding immunotherapy to new KRAS inhibitors boosted responses in preclinical models, setting the stage for future trials of the combination strategy. The study was published in Cancer Discovery by researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center. Perelman School of Medicine at the University of Pennsylvania