Granata Bio ("Granata") today announced the acquisition of Oviva Therapeutics, Inc. ("Oviva"), a pioneering women's health biotech company focused on advancing treatments that address female physiology, with an emphasis on ovarian aging.
Wild animals that have acquired adaptions to maximize their reproductive output in some of the worldâs most extreme conditions may provide answers to some of the most pressing problems in the field of human reproductive health.
CRCHUM researchers reveal that the guinea pig pre-implantation embryo is very similar to the human embryo, spurring a better understanding of infertility and early human development.
This study uncovers dynamic immune adaptations during pregnancy through single-cell RNA sequencing of peripheral blood mononuclear cells at different pregnancy stages. A gradual reduction in cytotoxicity of T and NK cells, along with decreased MHC-II and CD40 signaling in T and B cells, suggests weakened adaptive immunity. Meanwhile, upregulated pro-inflammatory genes in monocytes may compensate for this reduction. Late pregnancy shows a transition toward immune activation in dendritic and CD4+ T cells. Notably, we highlight a novel pro-aging effect of pregnancy, which may reverse postpartum. These findings enhance our understanding of pregnancy immunity and its impact on disease risk.
Recent data from Pew Research Center suggest that Americans are rethinking whether they want to become parents. This could be part of a long-term trend, as a research team from Michigan State University found that the percentage of nonparents in the United States who never want children has doubled over the past 20 years.
Introducing the KinderHELOC, the first ever fertility financing option designed to allow the 1 in 6 Americans with infertility tap the equity in their home to pay for fertility treatment and family building
At the start of the pandemic, Iona Woolmington was installing artwork at a contemporary art museum in downtown Chicago when she first began having trouble in the bathroom. Blood in her stool prompted the then 35-year-old to see a doctor, leading to a devastating diagnosis: stage 3 rectal cancer.
April is Testicular Cancer Awareness Month. Thomas L. Jang, MD, MPH, FACS, is chief of urologic oncology at Rutgers Cancer Institute and RWJBarnabas Health shares what young men need to know.
Fertility rates across the world have been steadily dropping since 1950. Pinpointing the reasons â despite the lack of typical causal conditions such as famine or war â is at the heart of one researcherâs work at the University of Notre Dame. Lakshmi Iyer, a professor in the Department of Economics, found that there was more to fertility rates than a simple economic or circumstantial explanation.
A major reorganization of the U.S. Department of Health and Human Services (HHS)âincluding massive cuts to the federal workforceâthreatens scientific progress that drives our economy and improves the publicâs health.
The success of in vitro fertilization depends on many factors, one of which is sperm viability. A recent study from the University of Illinois Urbana-Champaign documents a new way to select viable sperm and prolong their viability in the laboratory, reducing one source of variability during the process.
In new research, Jagadeesh Sivadasan, professor of business economics and public policy, and collaborators explore how Chinaâs one-child policy boosted female entrepreneurship.
The Endometriosis CARE Act, which was introduced in 2022, seeks to deliver $50 million annually to advance research and expand access to treatment for this condition in which tissue similar to the uterine lining grows outside the uterus, often causing pain, heavy periods and potential fertility issues.
Endocrine Society members elected Nanette Santoro, M.D., of the University of Colorado School of Medicine in Aurora, Colo., as its 2026-2027 President. She will serve as President-Elect for a year beginning in July 2025 before becoming President in June 2026.
A genetic mutation in mice affects cells required for sexual reproduction and holds clues about male infertility that could pave the way for new treatments and male contraceptives, a Rutgers UniversityâNew Brunswick researcher and colleagues have discovered.
Writing in Nature Communications, Devanshi Jain, an assistant professor with the Department of Genetics at the School of Arts and Sciences, addresses a fundamental question about how humans and animals develop germ cells that go on to form sperm.