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Released: 26-Mar-2024 3:05 PM EDT
Biotechnology CEO and Inventor of SiriusXM Satellite Radio Martine Rothblatt to Deliver Graduation Address to the University of Maryland School of Medicine’s 215th Graduating Class
University of Maryland School of Medicine

University of Maryland School of Medicine (UMSOM) Dean Mark T. Gladwin, MD, announced today that Martine Rothblatt PhD, JD, MBA, Chairperson and CEO of United Therapeutics, and inventor of SiriusXM Satellite Radio, will deliver the keynote address for this year’s graduating medical student class. The UMSOM MD graduation ceremony will take place at the Hippodrome Theatre on Thursday, May 16, 2024.

   
Released: 26-Mar-2024 12:00 PM EDT
Low-intensity pulsed ultrasound reduces alveolar bone resorption during orthodontic treatment via Lamin A/C-Yes-associated protein axis in stem cells
World Journal of Stem Cells

BACKGROUNDThe bone remodeling during orthodontic treatment for malocclusion often requires a long duration of around two to three years, which also may lead to some complications such as alveolar bone resorption or tooth root resorption. Lo

Released: 26-Mar-2024 12:00 PM EDT
O-linked β-N-acetylglucosaminylation may be a key regulatory factor in promoting osteogenic differentiation of bone marrow mesenchymal stromal cells
World Journal of Stem Cells

Cumulative evidence suggests that O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) plays an important regulatory role in pathophysiological processes. Although the regulatory mechanisms of O-GlcNAcylation in tumors have been graduall

Released: 26-Mar-2024 12:00 PM EDT
Evaluation of genetic response of mesenchymal stem cells to nanosecond pulsed electric fields by whole transcriptome sequencing
World Journal of Stem Cells

BACKGROUNDMesenchymal stem cells (MSCs) modulated by various exogenous signals have been applied extensively in regenerative medicine research. Notably, nanosecond pulsed electric fields (nsPEFs), characterized by short duration and high st

Released: 26-Mar-2024 12:00 PM EDT
Long-term outcome of stem cell transplantation with and without anti-tumor necrotic factor therapy in perianal fistula with Crohn’s disease
World Journal of Stem Cells

BACKGROUNDStem cell transplantation is a promising therapeutic option for curing perianal fistula in Crohn’s disease (CD). Anti-tumor necrotic factor (TNF) therapy combined with drainage procedure is effective as well. However, previous s

Released: 26-Mar-2024 12:00 PM EDT
Understanding host-graft crosstalk for predicting the outcome of stem cell transplantation
World Journal of Stem Cells

Mesenchymal stromal cells (MSCs) hold great promise for tissue regeneration in debilitating disorders. Despite reported improvements, the short-term outcomes of MSC transplantation, which is possibly linked to poor cell survival, demand ext

Released: 26-Mar-2024 12:00 PM EDT
Self-assembly of differentiated dental pulp stem cells facilitates spheroid human dental organoid formation and prevascularization
World Journal of Stem Cells

BACKGROUNDThe self-assembly of solid organs from stem cells has the potential to greatly expand the applicability of regenerative medicine. Stem cells can self-organise into microsized organ units, partially modelling tissue function and re

Released: 26-Mar-2024 12:00 PM EDT
How mesenchymal stem cells transform into adipocytes: Overview of the current understanding of adipogenic differentiation
World Journal of Stem Cells

Mesenchymal stem cells (MSCs) are stem/progenitor cells capable of self-renewal and differentiation into osteoblasts, chondrocytes and adipocytes. The transformation of multipotent MSCs to adipocytes mainly involves two subsequent steps fro

Released: 26-Mar-2024 12:00 PM EDT
High glucose microenvironment and human mesenchymal stem cell behavior
World Journal of Stem Cells

High glucose (HG) culture conditions in vitro and persistent exposure to hyperglycemia in diabetes patients are detrimental to stem cells, analogous to any other cell type in our body. It interferes with diverse signaling pathways, i.e. mam

Newswise: Psilera Welcomes Biopharma Executive Dr. Magali Haas to its Board of Directors
Released: 26-Mar-2024 9:00 AM EDT
Psilera Welcomes Biopharma Executive Dr. Magali Haas to its Board of Directors
Psilera

Psilera, a leading biotechnology company developing groundbreaking therapies for hard-to-treat neurological disorders, is pleased to announce the appointment of Magali Haas, M.D., Ph.D., to its esteemed Board of Directors.

   
Released: 21-Mar-2024 2:05 PM EDT
Penn Scientists Create Novel Technique to Form Human Artificial Chromosomes
Perelman School of Medicine at the University of Pennsylvania

Human artificial chromosomes (HACs) capable of working within human cells could power advanced gene therapies, including those addressing some cancers, along with many laboratory applications, though serious technical obstacles have hindered their development.

Released: 21-Mar-2024 9:00 AM EDT
Kazia Therapeutics licenses paxalisib to Sovargen for intractable seizures in rare central nervous system diseases
Kazia Therapeutics Limited

Kazia Therapeutics Limited (NASDAQ: KZIA), a biotechnology company specialising in oncology, is pleased to announce that it has entered into an exclusive licensing agreement with Sovargen Co., Ltd, a biotechnology company specializing in central nervous system (CNS) diseases, to develop, manufacture and commercialise paxalisib as a potential treatment of intractable epilepsy in focal cortical dysplasia type 2 (FCD T2) and tuberous sclerosis complex (TSC) disease.

   
Newswise: It’s Hearty, It’s Meaty, It’s Mold
Released: 14-Mar-2024 6:00 AM EDT
It’s Hearty, It’s Meaty, It’s Mold
Lawrence Berkeley National Laboratory

Fungi naturally produce all the ingredients needed for a cruelty-free meat substitute. Our scientists are exploring how tuning the genomes of mushrooms and molds can transform these food sources into gourmet, nutrient-packed meals made with minimal processing and a light environmental footprint.

Newswise: Cows to the rescue for diabetics? Transgenic cow produces human insulin in milk
Released: 13-Mar-2024 11:05 AM EDT
Cows to the rescue for diabetics? Transgenic cow produces human insulin in milk
College of Agricultural, Consumer and Environmental Sciences, University of Illinois Urbana-Champaign

An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk.

Newswise: Prize of the Leopoldina for young scientist Jingyuan Xu from KIT
Released: 12-Mar-2024 7:05 AM EDT
Prize of the Leopoldina for young scientist Jingyuan Xu from KIT
Karlsruhe Institute of Technology (KIT)

With the Leopoldina Prize for young scientists 2023, German National Academy of Sciences Leopoldina honors Dr. Jingyuan Xu, who researches novel heating and cooling technologies for the energy transition at Karlsruhe Institute of Technology (KIT). Currently, the young engineer can boast two more significant awards: the Hector RCD Award as well as admission to the Global Young Academy, an exclusive association of international young scientists.

Newswise: This Injectable Hydrogel Mitigates Damage to the Right Ventricle of the Heart
29-Feb-2024 7:00 AM EST
This Injectable Hydrogel Mitigates Damage to the Right Ventricle of the Heart
University of California San Diego

An injectable hydrogel can mitigate damage to the right ventricle of the heart with chronic pressure overload, according to a new study published March 6 in Journals of the American College of Cardiology: Basic to Translational Science.  The study, by a research team from the University of California San Diego, Georgia Institute of Technology and Emory University, was conducted in rodents.

Newswise:Video Embedded celebrating-25-years-a-qa-with-ceo-gunther-eysenbach
VIDEO
Released: 5-Mar-2024 9:15 AM EST
Celebrating 25 Years: A Q&A With CEO Gunther Eysenbach
JMIR Publications

In this new video, Eysenbach shares the origins of the Journal of Medical Internet Research and the driving forces that led him to establish an open access digital health journal. His passion for publishing, coupled with a background in medicine and information and computer science, fueled his vision to leverage the internet's transformative power in making medical information accessible to both professionals and consumers.

   
Released: 5-Mar-2024 9:00 AM EST
Dive into the future of molecular life sciences at #DiscoverBMB 2024
American Society for Biochemistry and Molecular Biology (ASBMB)

Discover BMB, the annual meeting of the American Society for Biochemistry and Molecular Biology will be held March 23–26 in San Antonio. Secure your front-row seat to cutting-edge findings, approaches and technologies in the biological sciences by registering for a complimentary press pass to attend in person or to access press materials electronically.

Newswise: Lab-grown liver organoid to speed up turtle research, making useful traits easier to harness
Released: 4-Mar-2024 5:05 PM EST
Lab-grown liver organoid to speed up turtle research, making useful traits easier to harness
Iowa State University

A team of Iowa State University researchers developed protocols for growing organoids that mimic a turtle liver, the first organoids developed for a turtle and only the second for any reptile. The discovery will aid deeper study of turtle genetics, including the cause of traits with potential medical applications for humans such as the ability to survive weeks without oxygen.

Released: 4-Mar-2024 2:05 PM EST
UC Irvine receives $15 million NSF grant for integrative movement research
University of California, Irvine

The National Science Foundation has granted $15 million to the Integrative Movement Sciences Institute at the University of California, Irvine. This six-year funding, part of the NSF’s Biology Integration Institutes program, will support groundbreaking research led by Monica Daley, professor of ecology & evolutionary biology at the UCI School of Biological Sciences.

Newswise: Registration open for all LLNL summer education programs
Released: 4-Mar-2024 1:05 PM EST
Registration open for all LLNL summer education programs
Lawrence Livermore National Laboratory

Registration is now open for Lawrence Livermore National Laboratory’s summer education programs.

Newswise: EcoFABs Could Lead to Better Bioenergy Crops
Released: 29-Feb-2024 11:00 AM EST
EcoFABs Could Lead to Better Bioenergy Crops
Lawrence Berkeley National Laboratory

A greater understanding of how plants and microbes work together to store vast amounts of atmospheric carbon in the soil will help in the design of better bioenergy crops for the fight against climate change. Deciphering the mechanics of this mutually beneficial relationship is, however, challenging as conditions in nature are extremely difficult for scientists to replicate in the laboratory. To address this challenge, researchers created fabricated ecosystems or EcoFABs.

Released: 27-Feb-2024 8:05 PM EST
Five Cutting-edge Advances in Biomedical Engineering and Their Applications in Medicine
University of California San Diego

Bridging precision engineering and precision medicine to create personalized physiology avatars. Pursuing on-demand tissue and organ engineering for human health. Revolutionizing neuroscience by using AI to engineer advanced brain interface systems. Engineering the immune system for health and wellness. Designing and engineering genomes for organism repurposing and genomic perturbations.

Newswise: ReadCube Expands Its Award-Winning Literature Management Platform with the Launch of Literature Review
Released: 27-Feb-2024 9:00 AM EST
ReadCube Expands Its Award-Winning Literature Management Platform with the Launch of Literature Review
Digital Science and Research Solutions Ltd

Digital Science is pleased to announce that ReadCube, an award-winning leader in literature management and full-text document delivery, has launched a new solution for research-driven organizations – known simply as Literature Review by ReadCube.

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Newswise: ReadCube Expands Its Award-Winning Literature Management Platform with the Launch of Literature Review
Released: 27-Feb-2024 9:00 AM EST
ReadCube Expands Its Award-Winning Literature Management Platform with the Launch of Literature Review
Digital Science and Research Solutions Ltd

Digital Science is pleased to announce that ReadCube, an award-winning leader in literature management and full-text document delivery, has launched a new solution for research-driven organizations – known simply as Literature Review by ReadCube.

       
Newswise: High production of polyols using crude glycerol by wild-type safe yeasts
Released: 26-Feb-2024 7:05 AM EST
High production of polyols using crude glycerol by wild-type safe yeasts
Chinese Academy of Sciences

Utilization of crude glycerol generated as a by-product from biodiesel production process, for the production of high value-added products, represents an opportunity to overcome the negative impact of low glycerol prices in the biodiesel industry. In the present investigation, alternative ways of valorization of crude glycerol have been provided, by using this renewable material as substrate by natural yeasts of the Generally Recognized As Safe (GRAS) species Yarrowia lipolytica.

Newswise: Vlasov and Bashir groups develop nanoscale device for brain chemistry analysis
Released: 23-Feb-2024 2:05 PM EST
Vlasov and Bashir groups develop nanoscale device for brain chemistry analysis
University Of Illinois Grainger College Of Engineering

The device, developed by researchers at the University of Illinois Urbana-Champaign, is silicon-based and takes advantage of techniques developed for microelectronics manufacturing.

   
Newswise:Video Embedded raising-the-bar-for-medical-ai
VIDEO
Released: 23-Feb-2024 12:05 PM EST
Raising the Bar for Medical AI
Harvard Medical School

From the invention of the wheel to the advent of the printing press to the splitting of the atom, history is replete with cautionary tales of new technologies emerging before humanity was ready to cope with them.

Newswise: UAH researcher wins 2024 Worthington Medal for innovations in pumping sciences
Released: 21-Feb-2024 10:05 AM EST
UAH researcher wins 2024 Worthington Medal for innovations in pumping sciences
University of Alabama Huntsville

Dr. Phillip Ligrani, Eminent Scholar in Propulsion at The University of Alabama in Huntsville (UAH), has won the 2024 American Society of Mechanical Engineers (ASME) Henry R. Worthington Medal for developing innovative micro, millimeter and macro-scale pumping devices. Ligrani’s innovations are beneficial to a variety of applications, such as transporting biological samples without significant alteration or destruction of cells, and supplying coolant to maintain the temperatures of components subject to thermal loading, like lasers.

Newswise: Membrane Technology: Looking Deep into Smallest Pores
Released: 21-Feb-2024 4:05 AM EST
Membrane Technology: Looking Deep into Smallest Pores
Karlsruhe Institute of Technology (KIT)

Membranes of vertically aligned carbon nanotubes (VaCNT) can be used to clean or desalinate water at high flow rate and low pressure. Recently, researchers of Karlsruhe Institute of Technology (KIT) and partners carried out steroid hormone adsorption experiments to study the interplay of forces in the small pores. They found that VaCNT of specific pore geometry and pore surface structure are suited for use as highly selective membranes. The researchers report in Nature Communications. (DOI: 10.1038/s41467-024-44883-2)

Newswise: Junk DNA in birds may hold key to safe, efficient gene therapy
Released: 21-Feb-2024 2:05 AM EST
Junk DNA in birds may hold key to safe, efficient gene therapy
University of California, Berkeley

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.

   
Released: 21-Feb-2024 2:05 AM EST
New model identifies drugs that shouldn’t be taken together
Massachusetts Institute of Technology (MIT)

Any drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line the GI tract help with this process, but for many drugs, it’s unknown which of those transporters they use to exit the digestive tract.

Newswise: Invasive weed could be turned into a viable economic crop
Released: 19-Feb-2024 6:05 PM EST
Invasive weed could be turned into a viable economic crop
University of South Australia

One of the most invasive Australian weeds is being touted as a potential economic crop, with benefits for the construction, mining and forestry industries, and potentially many First Nations communities.

Newswise: Company co-founded by Case Western Reserve University researcher named finalist in South by Southwest pitch competition
Released: 19-Feb-2024 4:05 PM EST
Company co-founded by Case Western Reserve University researcher named finalist in South by Southwest pitch competition
Case Western Reserve University

Dustin Tyler, the Kent H. Smith II Professor of Biomedical Engineering at CWRU’s Case School of Engineering, co-founded a company that restores for people the sensation of touch—with help from a set of electrical rings that fit snugly on users’ fingers—from a distance.

Newswise: New technology brings advanced blood imaging closer to the clinic
Released: 16-Feb-2024 10:05 AM EST
New technology brings advanced blood imaging closer to the clinic
National Institute of Biomedical Imaging and Bioengineering

The qualities of flowing blood, or hemodynamics, hold important insights into vascular diseases, but technological limitations have largely kept measurements of these properties out of reach in the clinic. Now, there may be a potential solution on the horizon.

Released: 15-Feb-2024 2:00 PM EST
UIC research helps create new antibiotic that evades bacterial resistance
University of Illinois Chicago

New drug inspired by images that captured how bacteria block antibiotic activity

   
Newswise: inhalable-extracellular-vesicle-delivery-of-il-12-mrna-to-treat-lung-cancer-promote-systemic-immunity_0.png
Released: 15-Feb-2024 12:05 AM EST
Study Finds New Inhalable Therapy is a Big Step Forward in Lung Cancer Research
Columbia University School of Engineering and Applied Science

Columbia Biomedical Engineer Ke Cheng has developed a technique that uses inhalation of exosomes, or nanobubbles, to directly deliver IL-12 mRNA to the lungs of mice.

Newswise: Ochsner Health physician granted NIH Trailblazer Award
Released: 14-Feb-2024 8:05 AM EST
Ochsner Health physician granted NIH Trailblazer Award
Ochsner Health

Dr. Hernan Bazan honored for innovation in non-opioid drug development amidst the opioid crisis.

Newswise: Johns Hopkins Medicine-Led Study Shows Rapid COVID-19 Tests Done at Home are Reliable
Released: 13-Feb-2024 11:00 PM EST
Johns Hopkins Medicine-Led Study Shows Rapid COVID-19 Tests Done at Home are Reliable
Johns Hopkins Medicine

In a study involving nearly 1,000 patients seen at the Baltimore Convention Center Field Hospital (BCCFH) during a five-month period in 2022 — researchers at Johns Hopkins Medicine, the University of Maryland School of Medicine and five other collaborators report that a rapid antigen test (RAT) for detecting SARS-CoV-2, the virus that causes COVID-19, can be used at home with accuracy comparable to the same test being administered by a health care professional.

Newswise: Gold nanoparticles reverse brain deficits in multiple sclerosis, Parkinson’s
Released: 13-Feb-2024 10:05 AM EST
Gold nanoparticles reverse brain deficits in multiple sclerosis, Parkinson’s
UT Southwestern Medical Center

Results from phase two clinical trials at UT Southwestern Medical Center showed that a suspension of gold nanocrystals taken daily by patients with multiple sclerosis (MS) and Parkinson's disease (PD) significantly reversed deficits of metabolites linked to energy activity in the brain and resulted in functional improvements.

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5-Feb-2024 8:00 AM EST
3D Ice Printing can Create Artificial Blood Vessels in Engineered Tissue
Biophysical Society

Over 100,000 individuals in the United States are currently in need of organ transplants. The demand for organs, such as hearts, kidneys, and livers, far exceeds the available supply and people sometimes wait years to receive a donated organ.

   
Newswise: New Approach to Tackling Bacterial Infections Identified
5-Feb-2024 4:05 PM EST
New Approach to Tackling Bacterial Infections Identified
Mount Sinai Health System

Researchers at the Icahn School of Medicine at Mount Sinai have identified a new approach to controlling bacterial infections. The findings were described in the February 6 online issue of Nature Structural & Molecular Biology.

Newswise: UW-Milwaukee bioengineer creating a virtual tumor with data from an actual one
Released: 6-Feb-2024 11:05 AM EST
UW-Milwaukee bioengineer creating a virtual tumor with data from an actual one
University of Wisconsin-Milwaukee

Mahsa Dabagh is building a virtual model of a real human tumor, using data that characterizes the tissue on a molecular level.

Newswise: Pore power: high-speed droplet production in microfluidic devices
Released: 6-Feb-2024 10:05 AM EST
Pore power: high-speed droplet production in microfluidic devices
Chiba University

Over the past two decades, microfluidic devices, which use technology to produce micrometer-sized droplets, have become crucial to various applications.

Released: 6-Feb-2024 9:30 AM EST
Northwest Biotherapeutics Moves From Optimization of Flaskworks Prototype to Fabrication of GMP-Compliant Units For Installation, Validation and Final Testing Prior to Regulatory Certification
Northwest Biotherapeutics

Northwest Biotherapeutics (OTCQB: NWBO) ("NW Bio"), a biotechnology company developing DCVax® personalized immune therapies for solid tumor cancers, announced today that the key development work for the Flaskworks manufacturing system has been completed and an external vendor has been engaged to produce GMP-grade units of the system.

   
Newswise: Creating a Virus-Resistant Bacterium Using a Synthetic Engineered Genome
Released: 5-Feb-2024 4:05 PM EST
Creating a Virus-Resistant Bacterium Using a Synthetic Engineered Genome
Department of Energy, Office of Science

To improve bioproducts productivity, researchers have engineered the genome of E. coli to make it immune to viral infections.

   
Newswise: wawryzneic-wawosz-dobrucki-(left)-alongside-liviu-mirica-(center)-and-dr.-daniel-llano-.jpg?sfvrsn=ef50eef8_1
Released: 5-Feb-2024 3:05 PM EST
Better together: Beckman imaging facilities share $3M Alzheimer’s research grant
Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign

Beckman researchers and collaborators received $3 million from the U.S. National Institute on Aging to develop diagnostic tools and imaging agents for the early detection of Alzheimer’s disease.

   
Newswise: IU surgeon-scientist studying physiological effect of microorganisms in sinuses of chronic rhinosinusitis patients
Released: 2-Feb-2024 7:30 AM EST
IU surgeon-scientist studying physiological effect of microorganisms in sinuses of chronic rhinosinusitis patients
Indiana University

An Indiana University School of Medicine surgeon-scientist is leading a multi-institutional grant investigating the role of the sinus microbiome in chronic rhinosinusitis, an inflammatory disease that causes the lining of the sinuses to swell.

Released: 1-Feb-2024 10:05 PM EST
Resistant bacteria can remain in the body for years
University of Basel

Fighting disease-causing bacteria becomes more difficult when antibiotics stop working.



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