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Getting enough exercise can be especially helpful鈥攁nd especially challenging鈥攆or people with Parkinson鈥檚 disease. In a new study, patients who received a weekly email newsletter with Parkinson鈥檚-specific exercise tips saw a significant improvement in exercise capacity after 12 weeks.

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An international research collaboration led by Rutgers University-New Brunswick scientists that examined microscopic blobs of protein found in human cells has discovered that some morph from an almost honey-like substance to a hard candy-like solid. These mysterious droplets, known as biomolecular condensates, solidify when they carry a high proportion of the protein alpha-synuclein, the scientists reported in Science Advances. Clumps of alpha-synuclein are commonly found in the brain cells of people with Parkinson鈥檚 disease, a neurodegenerative brain disorder.

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A groundbreaking open-source computer program uses artificial intelligence to analyze videos of patients with Parkinson's disease and other movement disorders. The tool, called VisionMD, helps doctors more accurately monitor subtle motor changes, improving patient care and advancing clinical research.

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The latest research advances from Cedars-Sinai investigators.

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The Focused Ultrasound Foundation today announced a historic achievement for the field of noninvasive medicine: more than one million patients worldwide have now been treated with focused ultrasound.

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Scientists at Johns Hopkins Medicine say they have discovered how a group of proteins linked to Parkinson鈥檚 disease and amyotrophic lateral sclerosis act as 鈥済uardians鈥� of mitochondria, small organelles, or subunits, within a cell that make and store energy and are found in almost all plants and animals.

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NASA Awards NSCF $3.1M to Continue Studying Effects of Microgravity on Brain Cells

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As March Madness sweeps the nation and college basketball takes center stage, a former coach鈥檚 journey off the court is proving just as inspiring as any Cinderella story on the hardwood.聽Billy Kennedy, former head coach of Texas A&M, has spent his career developing game plans, mentoring players, and leading teams through the highs and lows of competition.

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The brains of babies delivered before 37 weeks鈥� gestation show weaker neural connections between key brain regions compared with those of full-term infants, a recent Cedars-Sinai study shows.

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A stem cell therapy trial aimed at reducing neuroinflammation in patients with presymptomatic Alzheimer鈥檚 disease is underway at UTHealth Houston.

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Pesquisadores da Mayo Clinic descobriram uma nova maneira de detectar e monitorar com mais precis茫o a atividade das c茅lulas cerebrais durante a estimula莽茫o cerebral profunda, um tratamento comum para dist煤rbios do movimento, como鈥痑 doen莽a de Parkinson鈥痚 tremor. Essa precis茫o pode ajudar os m茅dicos a ajustar a coloca莽茫o e a estimula莽茫o dos eletrodos em tempo real, proporcionando um atendimento melhor e mais personalizado aos pacientes que recebem o procedimento cir煤rgico. O鈥痚studo鈥痚st谩 publicado no Journal of Neurophysiology.

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Investigadores de Mayo Clinic han descubierto una nueva manera de detectar y monitorear con mayor precisi贸n la actividad de las c茅lulas cerebrales durante la estimulaci贸n cerebral profunda, un tratamiento com煤n para los trastornos del movimiento como la enfermedad de Parkinson鈥痽 temblor. Esta precisi贸n puede ayudar a los m茅dicos a ajustar la colocaci贸n y la estimulaci贸n de los electrodos en tiempo real, brindando una atenci贸n mejor y m谩s personalizada a los pacientes que reciben el procedimiento quir煤rgico. El鈥痚studio鈥痵e publica en Journal of Neurophysiology.

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Mayo Clinic researchers have found a new way to more precisely detect and monitor brain cell activity during deep brain stimulation, a common treatment for movement disorders such as鈥疨arkinson's disease鈥痑nd tremor.

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Long-term and precise intracellular signal detection is critical for advancing our understanding of brain diseases and developing effective diagnostic tools. A breakthrough method has been introduced to enhance the stability and fidelity of recording signals at the single-cell level using ultrafine electrodes (UME). By controlling the tip exposure of UMEs, researchers have demonstrated a significant improvement in their ability to resist environmental interference, thus improving signal-to-noise ratio and sensitivity, and the collection area has been precisely controlled. This method promises to enhance the performance of implantable neural interfaces for real-time monitoring of intracellular signals.

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UC Irvine School of Medicine podcast with Dr. Albert LaSpada on Ataxia

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People with obstructive sleep apnea have an increased risk of Parkinson鈥檚 disease, but if started early enough, continuous positive airway pressure (CPAP) may reduce that risk, according to a preliminary study released today, March 2, 2025, that will be presented at the American Academy of Neurology鈥檚 77th Annual Meeting taking place April 5鈥�9, 2025, in San Diego and online. The study found using CPAP within two years of a sleep apnea diagnosis reduced the risk of Parkinson鈥檚.

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Researchers at Washington University in St. Louis have found a critical role for the physical interfaces of amyloid beta peptides in determining the chemical dynamics of their assemblies.