New modeling research challenges public health guidelines that recommend conservative antibiotic use for cholera. In some cases, prescribing antibiotics more broadly could slow or stop outbreaks and even reduce the risk of antibiotic resistance.
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The pathogen that causes tuberculosis is deadly in part because of its complex outer envelope, which helps it evade immune responses of infected hosts. In an ACS Infectious Diseases paper, researchers developed a chemical probe to study a key component of this envelope. Their results provide a step toward finding new ways of inactivating the bacterium.
An experimental drug now in clinical trials as a cancer treatment could help boost the power of first-line tuberculosis (TB) treatments by helping infected cells die a gentler death, Johns Hopkins Medicine investigators report.
UdeM pharmacy professor Simon Matoori has reviewed studies on the therapeutic properties of honey in the treatment of both acute and chronic wounds.
Un estudio publicado en Brain Communications destaca un nuevo enfoque para el tratamiento de la epilepsia resistente a los medicamentos. Los investigadores de Mayo Clinic han desarrollado una plataforma innovadora de estimulación cerebral profunda (DBS, del inglés Deep Brain Stimulation) que se ha utilizado no solo para reducir las convulsiones, sino también para mejorar la memoria y el sueño, dos desafíos comunes para los pacientes con epilepsia.
Um estudo publicado na Brain Communications destaca uma nova abordagem para o tratamento da epilepsia resistente a medicamentos. Pesquisadores da Mayo Clinic desenvolveram uma plataforma inovadora de estimulação cerebral profunda ((DBS, do inglês Deep Brain Stimulation) que foi utilizada não apenas para reduzir as crises, mas também para melhorar a memória e o sono — dois desafios comuns para pacientes com epilepsia.
روتشستر، ولاية مينيسوتا — تسلِّط دراسة جديدة نُشرت في مجلة اتصالات الدماغ (Brain Communications) الضوء على طريقة جديدة لعلاج الصرع المقاوم للأدوية. طوّر الباحثون في مايو كلينك منصة مبتكرة للتحفيز العميق للدماغ والتي استُخدمت ليس فقط لتقليل النوبات، ولكن أيضًا لتحسين الذاكرة والنوم — وهما تحديان شائعان لمرضى الصرع.
A new study conducted by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has uncovered a key mechanism behind lenalidomide resistance in multiple myeloma (MM), offering new insights into potential strategies for improving treatment outcomes and overcoming drug resistance.
A study published in Brain Communications highlights a new approach to treating drug-resistant epilepsy. Researchers at Mayo Clinic have developed an innovative deep brain stimulation (DBS) platform that was used to not only reduce seizures, but also improve memory and sleep — two common challenges for patients with epilepsy.
Viruses known as “jumbo phage” are a new hope against the rising antibacterial infection crisis. Researchers have discovered how jumbo phage are able to infect bacteria so efficiently. They found a compartment that protects and hides valuable DNA material from the bacteria’s immune defense system.
A research team at Indiana University Bloomington has uncovered new details about how a tiny virus builds its protective outer shell —a crucial part of its ability to infect cells.
Antibiotic-resistant bacteria can cause life-threatening infections that are almost impossible to treat with existing medication. As a result, common illnesses such as urinary tract infections or skin wounds are becoming a health risk. Empa researchers are therefore working on sensors that quickly identify resistant germs and recommend efficient treatment.
A small molecule shaped like a lasso may be a powerful tool in the fight against infectious diseases, according to a new study in Nature co-authored by University of Illinois Chicago researchers.
A McMaster University team led by renowned researcher Gerry Wright has identified a strong candidate to challenge even some of the most drug-resistant bacteria on the planet: a new molecule called lariocidin.
Some notoriously difficult to treat infections may not be as resistant to antibiotics as has been thought, according to University of Illinois research using a microfluidic device that more closely duplicates the fluid flow found in the body.
The study, appearing in the March 25 edition of eBioMedicine (open-access journal from The Lancet), found that using intracranial EEG recordings with high-density arrays resulted in better appraisals and better agreement about the location of SOZ among the epileptologists, compared to lower-density recordings.
Irvine, Calif., Feb. 24, 2025 — There’s an arms race in medicine – scientists design drugs to treat lethal bacterial infections, but bacteria can evolve defenses to those drugs, sending the researchers back to square one. In the Journal of the American Chemical Society, a University of California, Irvine-led team describes the development of a drug candidate that can stop bacteria before they have a chance to cause harm.
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