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Traditional methods of studying human gene mutations are often laborious and costly. Now bioengineers at UC San Diego have developed a new simple approach to rapidly check on human gene changes and also screen chemicals as potential drugs by turning everyday bacteria into living test tubes.
After reviewing hundreds of hours of surgical video, a team led by Cedars-Sinai investigators has created a system that links specific steps performed during a surgical procedure to how well patients recover.
When we think of nature play, we envision children swinging from trees, decorating mud pies with gum nuts, and delving through creek beds. But nature play must be more than this and needs to cater to children of all ages and capabilities, say researchers at the University of South Australia.
Social workers in First Nations communities need to incorporate Aboriginal ways of knowing, being and doing at the heart of their supervision practices on Country.That’s the recommenda...
Hackensack Meridian Health Hospitals named to Newsweek's best maternity hospitals
Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania announced the first ever direct approach to the depletion and replacement of microglia, the native immune cells of the central nervous system (CNS). The approach leverages microglial replacement in Krabbe disease to demonstrate its broader therapeutic potential across other neurological conditions. The preclinical findings were published in the journal Immunity.
Researchers from UC San Diego found that Mindfulness-Oriented Recovery Enhancement (MORE) can help rewire the brain’s response to natural healthy pleasure, leading to reduced opioid cravings. The findings suggest that MORE could be a promising tool in the fight against opioid use disorder.
Finding has implications for treating common neuropsychiatric disorders
In a rare collaboration with geneticists and archaeologists, a federally recognized tribe in the United States has utilized ancient DNA to establish a genetic link to an important ancestral heritage site, Pueblo Bonito in Chaco Canyon.
Early fruit ripening is a valuable trait for grape cultivation, but the underlying epigenetic mechanisms have remained elusive. A new study uncovers how CHH site hypermethylation influences the early ripening phenotype of 'Fengzao', a bud mutant of the popular 'Kyoho' grape. Using whole-genome bisulfite sequencing, researchers demonstrated that higher promoter methylation, particularly at the JOX1 gene, plays a critical role in accelerating ripening. These findings offer fresh insights into the epigenetic regulation of berry development and could inform strategies to control fruit ripening in viticulture.
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