Researchers at Moffitt Cancer Center have found that tapping into the body’s own immune system and activating a type of immune cell known as B cells, could be the key to boosting the effectiveness of tumor-infiltrating lymphocyte, or TIL therapy. Results of their study were published in the Journal for Immunotherapy of Cancer.
Physician-scientist Theodore Scott Nowicki, MD, PhD, an assistant professor-in-residence of pediatric hematology/oncology and microbiology, immunology, & molecular genetics at the David Geffen School of Medicine at UCLA, has been awarded a $4.5 million R37 MERIT Award to help improve the effectiveness of cellular therapies for solid tumors.
The immune system typically can ramp up the body’s defenses to clear out an invading threat without issue. Glitches can happen, however, with sepsis occurring when the mustered army of cells also attacks the body’s own tissues and organs as if they were enemy combatants.
Using the microscopic structures found on the wings of the Morpho butterfly, researchers have developed a simple and inexpensive way to analyze cancer biopsy samples that could make cancer diagnosis faster, more accurate and more accessible worldwide.
A Penn Medicine pilot study shows it’s possible to use digital technology to safely reduce the amount of time some patients with cancer spend receiving care.
A recent study from researchers at Wake Forest University School of Medicine and Rutgers University shows a high rate of underage tobacco sales despite federal legislation that prohibits the sale of tobacco products to anyone under the age of 21.
W. Kimryn Rathmell, MD, PhD, MHHC, announced today that she is stepping down from her role as director of the National Cancer Institute (NCI), effective Monday, January 20. AACI extends is deep appreciation to Dr. Rathmell for her service as NCI director.
Federal science agencies have renewed and increased funding for a world-renowned digital archive of protein structures housed by Rutgers University-New Brunswick, an open-access data resource that has enabled research in everything from agriculture to zoology and has laid the groundwork for Nobel Prize-winning discoveries.
An experimental blood test for pancreatic cancer is being evaluated by a commercial laboratory, an important milestone toward making the test available for patients.
In an effort to greatly expand accessibility, this compact fluorescence-guided surgery system, evaluated in mice, is crafted from cost-effective and off-the-shelf components.
Patients with advanced cancer who also had cardiac defibrillators were more likely than those without these implants to receive aggressive end-of-life care, a team led by UT Southwestern Medical Center researchers found in a new study. The findings, published in Cancer, could help physicians guide patients in this growing population toward care that better matches their goals.
Keck Medicine of USC is participating in a national, multisite clinical trial examining if a water vapor system that uses small, targeted amounts of steam to kill cancer cells is a safe and effective treatment for prostate cancer.
A team of researchers at Roswell Park , led by Dhyan Chandra, PhD, has discovered a new therapeutic target for neuroendocrine prostate cancer, a rare and hard-to-treat form of prostate cancer. Their findings, newly published in the journal Oncogene, suggest that a set of processes known as the mitochondrial unfolded protein response, could be an Achilles’ heel for this often-deadly cancer type, and may point the way to a new treatment approach.
Washington University School of Medicine in St. Louis has received a renewal of a prestigious research grant from the National Cancer Institute. Led by principal investigator, Daniel Link, MD, the Specialized Program of Research Excellence (SPORE) grant in leukemia provides funding for translational research.
In a new study involving interviews of people with long COVID, researchers describe how the prolonged illness has affected not only patients’ job status, but also their overall well-being.
The federally funded pathway programs strive to increase diversity and equity in the cancer research field, a key strategy to reduce health disparities in the Chicagoland area and across the country.
Scientists at St. Jude Children’s Research Hospital leveraged fundamental features of chemical building blocks to transform chemical reaction analysis from minutes to milliseconds.
Teal Health, a woman-led company on a mission to get all women and people with a cervix in the US screened for cervical cancer, has been awarded a $1.68 million Small Business Innovation Research (SBIR) Direct to Phase II Grant from the National Cancer Institute (NCI) of the National Institutes of Health (NIH).
Updated results from a phase 3 clinical trial are expected to change the way advanced stage classic Hodgkin lymphoma (cHL) is treated. Details appear in a study published today in The New England Journal of Medicine. Drs. Kara Kelly of Roswell Park Comprehensive Cancer Center and Sharon Castellino of Children’s Healthcare of Atlanta and Emory University School of Medicine/Winship Cancer Institute of Emory University served as pediatric leads of this important trial in children and adults with lymphoma.
The findings, published in the Journal of the National Cancer Institute, show that markers of cellular aging—such as DNA damage response, cellular senescence, and inflammatory pathways—significantly increased in all breast cancer survivors, regardless of the type of treatment received.
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